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Understanding Psoriasis
Psoriasis is a chronic autoimmune condition that results in the rapid growth of skin cells, leading to scaling on the skin's surface. It can cause red patches of skin covered with thick, silvery scales, and it is often itchy and sometimes painful. Psoriasis can occur anywhere on the body, but is commonly found on the elbows, knees, scalp, and lower back.
What is Skyrizi?
Skyrizi (risankizumab) is a monoclonal antibody approved for the treatment of moderate to severe plaque psoriasis in adults. It works by targeting and inhibiting the action of interleukin-23 (IL-23), a protein involved in inflammatory processes. By blocking IL-23, Skyrizi helps to reduce inflammation and the overproduction of skin cells associated with psoriasis.
Indications for Skyrizi Use
Skyrizi is indicated for adults with moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy. It is especially recommended for individuals who have not responded well to other treatments, including topical therapies or phototherapy. Patients should consult their healthcare provider to determine if Skyrizi is appropriate for their condition.
Dosage and Administration
The recommended dosage of Skyrizi is 150 mg administered by subcutaneous injection. Initial treatment includes two doses of 150 mg, given 4 weeks apart, followed by a maintenance dose of 150 mg every 12 weeks. Patients should be instructed on the proper technique for self-administering the injection and should not attempt to modify their dosing schedule without consultation.
Possible Side Effects
Common side effects of Skyrizi include injection site reactions, headaches, and fatigue. Serious side effects may include allergic reactions, infections, and changes in liver function tests. Patients are encouraged to report any unusual symptoms or side effects to their healthcare provider immediately.
Lifestyle and Supportive Measures
In addition to medication, adopting a healthy lifestyle can positively affect psoriasis outcomes. This includes stress management techniques, maintaining a balanced diet, staying hydrated, and engaging in regular physical activity. Support groups and counseling may also provide additional assistance for coping with the psychological aspects of living with psoriasis.
Conclusion
Skyrizi offers a promising treatment option for individuals suffering from moderate to severe plaque psoriasis. It is crucial to follow healthcare provider recommendations and maintain regular check-ups for effective management of the condition. Patients should always feel empowered to communicate openly with their healthcare team about their treatment preferences and concerns.